Prepare your proposal the way IRB reviewers expect.
Institution-verified templates built from real approved submissions — turning IRB prep into a clear, guided process that saves you weeks.
Not sure if your project needs IRB review? Start here to find your path.
Already know you need IRB? Jump straight to Protocol Design Assistant or browse templates.
Skip the Form,
Start with a Conversation
Answer 8-12 smart questions about your study, and watch as ClearPath automatically fills in proposal fields for you.
Generate Your Protocol
Draft in Minutes
Answer 8 guided questions and receive a professional 5-paragraph IRB protocol draft written by ClearPath.
From Blank Page to Submission-Ready
Every feature is designed to help you understand what review boards expect and design stronger protocols—no guesswork, no missing requirements.
Last updated: Oct 2025
Institution-Verified Templates
Stop searching through hundreds of pages of IRB guidelines. Our templates are built from actual approved protocols—you get exactly what your committee expects to see.
See How We VerifyMulti-Site Research
Running a study across multiple sites? Create one unified proposal that satisfies both IRBs. No more copying and pasting the same information into different formats.
Learn MoreCatch Errors Before Review
Real-time validation checks your proposal against IRB requirements as you type. Find missing information and compliance issues before your committee does.
See ValidationSubmit in Minutes, Not Hours
Download your completed proposal as a professionally formatted DOCX or PDF. No copying into Word, no fixing margins, no formatting headaches.
See ExamplesSmart Templates
Choose from IRB-compliant templates specifically designed for different research types. Each template includes validated fields mapped directly to regulatory requirements.
Available Templates:
- Survey Research: Minimal risk studies with anonymous or coded data collection (45 CFR 46.110 expedited review eligible)
- Vulnerable Populations: Enhanced protections for children, prisoners, and cognitively impaired subjects (Subparts B, C, D)
- Observational Studies: Non-interventional research with HIPAA-compliant data handling (§164.514)
Real-time Validation
Get instant feedback as you complete your proposal. Our validation engine checks your work against IRB requirements in real-time, catching issues before submission.
What We Validate:
- Required field completion
- Regulatory compliance per 45 CFR 46
- Character limits and formatting rules
- Logic consistency (e.g., sample size justification)
- HIPAA privacy rule adherence for applicable studies
Pro Tip: Validation results show both errors (must fix) and warnings (recommended improvements) so you know exactly what needs attention.
Export Options
Export your completed proposal as a professionally formatted document ready for institutional submission. All formatting, headers, and structure are applied automatically.
Format Options:
- Word (DOCX): Editable format for additional customization or tracked changes
- PDF: Final, locked format ideal for official submissions and archiving
Automatic Formatting Includes:
- Professional title page with PI information
- Properly structured sections with headings
- Institutional naming convention (IRB_[LastName]_[Title]_[Date])
- All required metadata and compliance documentation
Collaboration
Share your proposal draft with advisors, co-investigators, or compliance officers for review without granting edit access. Perfect for getting feedback before final submission.
How It Works:
- Generate a unique, secure review link for each draft
- Reviewers see a read-only view with all proposal details
- Validation status is visible so reviewers know if it's submission-ready
- Links remain active while your proposal is in draft status
- No login required for reviewers - just share the link
Use Case: Send to your faculty advisor for preliminary review, IRB coordinator for pre-submission check, or department chair for approval before submission.
Privacy First
Choose how your data is stored. We offer Local Mode for maximum privacy, keeping all your proposal data exclusively in your browser with zero cloud storage.
Two Storage Options:
Cloud Mode (Default)
Data saved to secure database, enables validation, export, and sharing features.
Local Mode
All data stored only in your browser's localStorage. Maximum privacy, but validation/export/sharing disabled.
Auto-Save
Never lose your work. Every change you make is automatically saved within 1 second, whether you're in Cloud Mode or Local Mode.
How Auto-Save Works:
- Changes debounced to 1 second after you stop typing
- Visual confirmation when save completes
- Works seamlessly across all form fields
- Continues even if you navigate between steps
- Respects your privacy choice (cloud or local storage)
Manual Version Control:
Need to save a specific milestone? Use the "Save Version" feature to create named snapshots with notes. Perfect for before major revisions or when seeking advisor approval.
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